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  • Test Details
  • Lab Values
  • Clinical Significance
  • Treatment Options
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Test Code 221

Test Details

High Density Lipoprotein Cholesterol (HDL-C)

HDL-C is a measure of high density cholesterol particles. Higher levels of HDL are associated with reduced CVD risk, but not all HDL is good. Refer to the Boston Heart HDL Map® for more information.

Methodology

Enzymatic colorimetric.

Patient Preparation

None

Preferred Specimen

Green Top Tube
(Lithium Heparin plasma separator tube with gel)

Alternate Specimen

Dried Blood collected on an AdvanceDx 100 card

Transport Temperature

Refrigerated (ship on frozen cold packs)

Stability

Refrigerated: 8 days

Lab Values

Lab Values

High Density Lipoprotein Cholesterol (HDL-C)

Age Optimal Borderline Increased Risk
≤18 yrs Male and Female >45 mg/dL 40 – 45 mg/dL <40 mg/dL
>18 yrs Male >50 mg/dL 40 – 50 mg/dL <40 mg/dL
>18 yrs Female >60 mg/dL 50 – 60 mg/dL <50 mg/dL

 

Test Details
Clinical Significance

Clinical Significance

High Density Lipoprotein Cholesterol (HDL-C)

Low HDL-C is:

  • Independently associated with CVD risk.1
  • A  characteristic of the metabolic syndrome and insulin resistance.1

References: 

  1. Goff DC Jr, Lloyd-Jones DM, Bennett G, et al. 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;129(25 Suppl 2):S49-73.
Lab Values
Treatment Options

Treatment Options

High Density Lipoprotein Cholesterol (HDL-C)

  • Lifestyle modification
  • Statins
  • Niacin
  • Fibrates
  • Fish oil
  • Bile acid sequestrants
Clinical Significance