Test Code 1105
Test Details
Troponin T Gen 5 (Troponin T)
Troponins are structural proteins of cardiac myocytes that are released into circulation after cardiac myocyte cell damage providing earlier identification of myocardial injury.
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
Patient Preparation
N/A
Preferred Specimen
2.0 mL serum (1.0 mL minimum) collected in a lithium-heparin plasma tube containing separating gel (green-top)
Alternate Specimen
N/A
Transport Temperature
Refrigerated (ship on frozen cold packs)
Stability
Refrigerated: 6 days
Lab Values
Troponin T Gen 5 (Troponin T)
Female
- Optimal: ≤14 ng/L
- Increased Risk: >14 ng/L
- Alert: >30 ng/L
Male
- Optimal: ≤22 ng/L
- Increased Risk: >22 ng/L
- Alert: >33 ng/L
Clinical Significance
Troponin T Gen 5 (Troponin T)
- High Risk Troponin T may indicate a recent acute myocardial infarction (AMI). After ruling out AMI, elevated values may indicate a seven fold increased risk of cardiovascular disease (CVD) mortality over a 3-10 year period.
- NT‑proBNP and CRP in combination with Troponin T:
- Elevated values of Troponin T, NT-proBNP and CRP may indicate over a 10-fold increased risk of cardiovascular disease (CVD) mortality and 12-fold risk of stroke mortality over a 10 year period.
Treatment Options
Troponin T Gen 5 (Troponin T)
- Treatment is based on etiology of elevation.
- High values should be considered together with signs and symptoms, (i.e. chest pain, pressure, or tightness), electrocardiogram, stress test and/or other CVD diagnostic technologies.
