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- Test Details
- Lab Values
- Clinical Significance
- Treatment Options
Total iron binding capacity (TIBC) is a blood test to see if there is too much or too little iron in the blood.
TIBC is calculated as follows: Iron + UIBC
1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST / Tiger Top)
Refrigerated (ship on frozen cold packs)
Refrigerated: 7 days
- Low: <250 µg/dL
- Normal: 250-370 µg/dL
- High: >370 µg/dL
- Total iron-binding capacity (TIBC) is most frequently used along with a serum iron test to evaluate people suspected of having either iron deficiency or iron overload. TIBC + serum iron are used to calculate transferrin saturation.
- In iron deficiency, the iron level is low, the TIBC is increased, and the transferrin saturation becomes very low.
- In iron overload states (i.e. hemochromatosis), the iron level is high, TIBC will be low or normal, and the transferrin saturation is increased.
Treatment is based on etiology of elevation.