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  • Test Details
  • Lab Values
  • Clinical Significance
  • Treatment Options
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Test Code 648

Test Details

Spike Antibody (SARS-CoV-2 [COVID-19])

Spike Antibody measures the presence and amount of antibodies made against the spike protein in response to either virus exposure or mRNA vaccination.

Methodology

Electrochemiluminescent Immunoassay

Patient Preparation

None

Preferred Specimen

1.0 mL serum collected in a serum separator tube (SST / Tiger Top)

Alternate Specimen

N/A

Transport Temperature

Refrigerated (ship on frozen cold packs)

Stability

Refrigerated: 7 days

Lab Values

Lab Values

Spike Antibody (SARS-CoV-2 [COVID-19])

  • Values ≥0.80 U/mL are considered positive.
Test Details
Clinical Significance

Clinical Significance

Spike Antibody (SARS-CoV-2 [COVID-19])

This is an electrochemiluminescence immunoassay intended for qualitative and semi-quantitative detection of antibodies to SARS‐CoV‐2 spike (S) protein receptor binding domain (RBD) in human serum and plasma. The Elecsys Anti‐SARS‐CoV‐2 S assay is intended as an aid in identifying individuals with an adaptive immune response to SARS‐CoV‐2, indicating recent or prior infection. The Spike antibody also measures the immune response to the Pfizer and Moderna vaccines. This assay has no cross reactivity with antibodies for other coronavirus strains or other respiratory viruses.
 

  • The sensitivity and specificity of our COVID-19 antibody tests are >95%, with CVs of <4%

Reference

Roche Elecsys anti-SARS-CoV-2 S Package Insert

Lab Values
Treatment Options

Treatment Options

Spike Antibody (SARS-CoV-2 [COVID-19])

Symptomatic SARS-CoV-2 (COVID-19) infections usually resolve without treatment, and vaccination is recommended for prevention. Severe cases may require hospitalization and/or medical treatment.

Clinical Significance