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Test Code 1136
PTH is a hormone secreted by the parathyroid glands that is important in bone remodeling. PTH functions as part of a feedback system that involves calcium, phosphorus (as phosphate), and vitamin D.
Electrochemiluminescence Immunoassay (ECLIA)
1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST/Tiger Top)
Refrigerated (ship on frozen cold packs)
Refrigerated: 2 days
- Low: <15 pg/dL
- Normal: 15-65 pg/dL
- High: >65 pg/dL
- Used to help diagnose the cause of a low or high calcium level and to help distinguish between parathyroid-related and non-parathyroid-related causes.
- A calcium test is almost always ordered along with PTH to determine the balance between calcium and PTH and the response of the parathyroid glands to changing levels of calcium.
- Most often ordered when calcium regulation is abnormal.
- High doses of biotin (> 5 mg/day) may interfere with assay results. Patient assumed to be refraining from biotin supplementation for at least 3 days prior to blood draw.
- Primary hyperparathyroidism – Surgery to remove adenoma or parathyroidectomy
- Secondary hyperparathyroidism – Treat underlying cause/condition most often kidney disease. In some cases, medication may be used to reduce PTH secretion and/or high calcium levels in blood.
- Patients with hypoparathyroidism are treated with calcium and vitamin D supplementation.