Test Code 1145
Test Details
Gamma Glutamyl Transferase (GGT)
Gamma-glutamyl transferase (GGT) is used in the diagnoses and monitoring of hepatobiliary disorders such as fatty, alcoholic and chronic liver diseases.
Methodology
Enzymatic Colorimetric
Patient Preparation
N/A
Preferred Specimen
1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST / Tiger Top)
Alternate Specimen
N/A
Transport Temperature
Refrigerated (ship on frozen cold packs)
Stability
Refrigerated: 7 days
Lab Values
Gamma Glutamyl Transferase (GGT)
Female
- Optimal: <35 U/L
- Borderline: 35-70 U/L
- Increased Risk: >70 U/L
Male
- Optimal: <60 U/L
- Borderline: 60-120 U/L
- Increased Risk: >120 U/L
Clinical Significance
Gamma Glutamyl Transferase (GGT)
GGT is an indirect measure of increased oxidative stress and moderately elevated levels are associated with CVD, metabolic syndrome, type 2 diabetes, hypertriglyceridemia, and fatty liver disease. Significantly elevated or high risk values are observed in patients with chronic liver and alcoholic liver diseases.
Treatment Options
Gamma Glutamyl Transferase (GGT)
- Identify etiology of elevated GGT with additional diagnostic tests as indicated.
- Treatment is based on etiology of elevation.
