Test Code 1033
Test Details
Direct Bilirubin
Bilirubin is a protein and natural by-product of red blood cell breakdown. Measures amount of bilirubin formed in the liver to become water soluble.
Methodology
Photometric
Patient Preparation
None
Preferred Specimen
1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST/Tiger Top)
Transport Temperature
Refrigerated (ship on frozen cold packs)
Stability
Refrigerated: 7 days
Lab Values
Direct Bilirubin
- Normal: 0.0-0.3 mg/dL
- High: >0.3 mg/dL
Clinical Significance
Direct Bilirubin
- If direct bilirubin is elevated more than total bilirubin, there typically is a problem with decreased elimination of bilirubin by the liver cells.
- Elevated serum levels could indicate liver diseases such as hepatitis, cirrhosis, neoplasm or gall bladder disease.
- Low levels are generally not a concern and are not monitored.
Treatment Options
Direct Bilirubin
- The course of treatment is dependent on the cause of the jaundice. The determination of direct as well as total bilirubin is used in differentiating certain types of jaundice.