Explore this test

  • Test Details
  • Lab Values
  • Clinical Significance
  • Treatment Options
DOWNLOAD SPECIMEN PREP FLYER

Explore this test

Test Code 649

Test Details

Neutralizing Antibody (SARS-CoV-2 [COVID-19])

Neutralizing Antibody measures the presence and amount of antibodies that have been shown to kill the SARS- CoV-2 virus in cell-based assays.

Methodology

Chemiluminescent Immunoassay

Patient Preparation

None

Preferred Specimen

1.0 mL serum collected in a serum separator tube (SST / Tiger Top)

Alternate Specimen

N/A

Transport Temperature

Refrigerated (ship on frozen cold packs)

Stability

Refrigerated: 4 days

Lab Values

Lab Values

Neutralizing Antibody (SARS-CoV-2 [COVID-19])

  • Values ≥1.00 AU/mL are considered positive.
Test Details
Clinical Significance

Clinical Significance

Neutralizing Antibody (SARS-CoV-2 [COVID-19])

Neutralizing antibodies are a subset of antibodies that bind to the virus in a manner that blocks infection. A neutralizing antibody might block interactions with a cellular receptor, or bind to a viral capsid in a manner that inhibits the uncoating of the viral genome. Only a small subset of the many antibodies that bind a virus are capable of neutralization. This assay has no cross reactivity with antibodies for other coronavirus strains or other respiratory viruses.
 

  • The sensitivity and specificity of our COVID-19 antibody tests are >95%, with CVs of <4%.

Reference:

Diazyme Neutralizing Antibody Package Insert

Lab Values
Treatment Options

Treatment Options

Neutralizing Antibody (SARS-CoV-2 [COVID-19])

Symptomatic SARS-CoV-2 (COVID-19) infections usually resolve without treatment, and vaccination is recommended for prevention. Severe cases may require hospitalization and/or medical treatment.

Clinical Significance